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This medicine contains the active ingredient lornoxicam, which is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID).
HOW TO USE THIS PRODUCT:
Lornoxicam works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is an enzyme that is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and cause pain, swelling and inflammation. As lornoxicam stops the production of prostaglandins, it is effective at relieving pain and inflammation.
All the medicines in this group (NSAIDs) reduce inflammation caused by the bodys own immune system and are effective pain killers.
What is it used for?
Inflammatory disease of the joints (rheumatoid arthritis)
Osteoarthritis
Pain following surgery
Pain in the lower back and hip which travels down the back of the thigh into the leg (sciatica)
Warning!
Kidney function should be monitored in the following groups of people while taking this medicine: those over 65 years of age, obese people, those with impaired kidney function, high blood pressure or heart failure, those with stressed kidney function as a result of significant blood loss or severe dehydration and those who are to undergo major surgery.
People taking this medicine for longer than three months should have regular blood tests to monitor their blood count, kidney and liver functions.
People with liver diseases should have their liver function monitored regularly while taking this medicine.
Elderly people over 65 years of age should have their kidney and liver function monitored regularly while taking this medicine.
People who are obese or who have high blood pressure should have their blood pressure monitored regularly while taking this medicine.
This medicine should be taken before meals.
Use with caution in
Blood clotting disorders
Heart failure
High blood pressure (hypertension)
History of ulceration or bleeding in the stomach or intestines
Liver disease
Mild to moderately decreased kidney function
Obesity
People over 65 years of age
Not to be used in
Active peptic ulcer
Allergy to aspirin or other medicines in this class (NSAIDs)
Breastfeeding
Children or adolescents under 18 years of age
History of recurrent peptic ulcers
People in whom aspirin or other medicines in this class (NSAIDs), cause attacks of asthma, itchy rash (urticaria) or nasal inflammation (rhinitis)
Pregnancy
Severely decreased kidney function
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
The safety of this medicine during pregnancy has not been established, therefore it should not be used by pregnant women. Consult your doctor.
There is no information available about the safety of this medicine during breastfeeding. For this reason, the manufacturer states that it should not be used during breastfeeding. Seek medical advice from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Headache
Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain
Visual disturbances
Indigestion (dyspepsia)
Awareness of your heartbeat (palpitations)
Dizziness
Leg cramps
Sensation of ringing, or other noise in the ears (tinnitus)
Low red blood cell count (anaemia)
Alteration in taste
Excessive fluid retention in the body tissues, resulting in swelling (oedema)
Hair loss (alopecia)
Sleepiness (somnolence)
Weight changes
Increased bleeding time
Skin reactions such as itching, irritation, redness and rash
Ulceration or bleeding of the stomach or intestines
The side effects listed above may not include all of the side effects reported by the drugs manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
There may be an increased risk of bleeding if lornoxicam is taken with the following:
- blood-thinning or anticoagulant medicines such as warfarin
- antiplatelet medicines such as aspirin or clopidogrel
- corticosteroids such as prednisolone.
There is an increased risk of adverse effects if lornoxicam is taken with any other NSAID, eg ibuprofen.
Lornoxicam may reduce the effectiveness of the following medicines for high blood pressure:
- diuretics such as furosemide (frusemide)
- ACE inhibitors such as captopril
- beta-blockers such as propranolol.
Lornoxicam may increase the blood levels of the following medicines, resulting in an increased risk of side effects:
- lithium
- methotrexate
- digoxin.
Lornoxicam may increase the blood sugar lowering effect of sulphonylurea medicines for diabetes, eg glibenclamide.
There may be an increased risk of kidney problems if this medicine is taken with any of the following:
- diuretics
- ACE inhibitors
- ciclosporin.
Kidney function should be monitored in people taking lornoxicam with any of these medicines.
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